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Many experts reserve the use of diuretics for pregnant patients with cardiac disease or essential hypertension, due to the fact that diuretic use may decrease placental perfusion and the data do not indicate a positive benefit of diuretic use on the outcome of preeclampsia during pregnancy

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During the baseline arm, following an overnight fast, they were orally administered 2.5 mg midazolam HCl (2 mg/mL syrup